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JeanMarie Guenot, is a Pharmaceutical Business Executive with 20 years of experience in both the public and private sector with an emphasis in biotechnology and pharmaceutical industries. Her business experience has spanned the full spectrum of a company including, R&D, business development, venture capital and corporate and commercial development.


Her early positions in various companies from 1993 through 2009 helped to prepare her not only for her position as CEO with Amphivena, but as a successful entrepreneur when she started her own company.


In 2009, according to her bio, JeanMarie Guenot founded and ran SKS Ocular, an ophthalmic company. which focused on ocular drug delivery technologies and therapies for glaucoma, macular degeneration and ocular inflammation.


Currently she holds the position of president and CEO at Amphivena Therapeutics, Inc., a San Francisco based company that specializes in the development of immune therapies for bi-functional antibody therapy for blood cancer.


In June of 2015, under her leadership, Amphivena announced that their preclinical studies were able to identify the T-cell redirecting bispecific CD33/CD-targeting antibodies that met their activity and safety profile for treating AML (Acute Myeloid Leukemia). These findings were presented to the 2015 American Society of Clinical Oncology Annual Meeting.


Moreover, the positive preclinical results has lead to a milestone for Amphivena and Dr. Guenot. They have found AMV-564 as a viable therapeutic candidate for clinical development. They hope it will soon be ready for early phase clinical trials.


To understand the importance of this research, you must understand what it is and how Acute Myeloid Leukemia effects an individual. AML is a type of cancer of the blood where the bone marrow makes abnormal white blood cells, red blood cells or platelets. If not treated, it can progress quickly. The abnormal cells will build up in the bone marrow and blood, causing infection, anemia, and easy bleeding. These same leukemia cells can spread to other parts of the body, such as the gums, skin, brain, spinal cord and central nervous system.


As credited on Facebook, Dr. Guenot earned her MBA from The Wharton School at the University of Pennsylvania and her Ph.D from the University of California in San Francisco.


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